Calculate the consensus for a list of symbols using simple frequency fraction method. Normal (non-gap) symbols are given a weight of 100. The confidence of a symbol is the sum of weights for that symbol, divided by the total number of symbols occurring at that position. If symbols have confidence >= threshold, symbol corresponding to set of these high confidence symbols is used. If no symbol meets the threshold, symbol corresponding to set of all the symbols at that position is used.

For ambiguous symbols, the corresponding set of base symbols are retrieved. And for frequency calculation, each base symbol is given a weight of (100 / number of base symbols).

public class SimpleConsensusResolver : IConsensusResolver

Public Class SimpleConsensusResolver
	Implements IConsensusResolver

public ref class SimpleConsensusResolver : IConsensusResolver

type SimpleConsensusResolver =  
    class
        interface IConsensusResolver
    end